Biologique Recherche

Rescue Spa: The Original U.S. Spa & Online Retailer of Biologique Recherche

For over 20 years, Rescue Spa has been a leading U.S. destination for Biologique Recherche, proud to be the original spa and online retailer to introduce this iconic French professional skincare brand to American clients. Renowned for its raw active ingredients and transformative, treatment-level results, Biologique Recherche has been at the core of our facial philosophy from the very beginning. Today, cult essentials like Lotion P50, Masque Vivant, Creme Dermopurifiante, and Crème Iso-Placenta remain trusted staples for achieving clearer, smoother, more radiant skin.

Biologique Recherche
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130 products
  • Your Summer Glow Gift Awaits

    Your Summer Glow Gift Awaits

    Online only: Receive Danucera D7 Serum and a Danucera tote bag with any $350+ purchase online.

  • Front-facing unboxed product photo of Biologique Recherche Sérum Spectral 30ml on a clean background, showing serum bottle. Front-facing unboxed product photo of Biologique Recherche Sérum Spectral 8ml on a clean background, showing smaller serum bottle.
    biologique recherche
    Serum Spectral

    $85.00
    $85.00
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  • Shop Rescue Spa Biologique Recherche Lotion P50 exfoliating and purifying toner for face, 250ml bottle. Shop Rescue Spa Biologique Recherche Lotion P50 exfoliating and purifying toner for face, 150ml.
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    Lotion P50

    Exfoliating & Balancing Facial Toner

    $45.00
    $45.00
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  • Biologique Recherche Masque Vivant, rebalancing face mask, size 100 ml / 3.4 fl.oz
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    Masque Vivant

    Balancing Face Mask

    $95.00
    $95.00

    Add to cart
  • Biologique Recherche Lotion P50 PIGM 400 exfoliating and brightening face toner size 8.4oz Biologique Recherche Lotion P50 PIGM 400 exfoliating and brightening face toner size 5.1oz
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    Lotion P50 PIGM 400

    Brightening Toner for Pigmentation and Uneven Skin Tone

    $45.00
    $45.00
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  • Biologique Recherche Crème Dermopurifiante, Purifying Moisturizer for Oily, Acne-Prone Skin
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    Creme Dermopurifiante

    Purifying Moisturizer for Oily, Acne-Prone Skin

    $135.00
    $135.00

    Add to cart
  • Biologique Recherche Lotion P50W, a gentle exfoliating and purifying lotion for face Size 8.4 fl.oz Biologique Recherche Lotion P50W, a gentle exfoliating and purifying lotion for the face, Size 5.1 fl. oz
    biologique recherche
    Lotion P50W

    Gentle Exfoliating Toner

    $45.00
    $45.00
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  • Lotion P50V Lotion P50V exfoliating toner, 5.1 fl.oz. Medium white plastic bottle labeled "Lotion P50V" with dark blue text on a clean white background. This vitamin-enriched toner gently exfoliates dead skin cells, balances pH, hydrates, and refines skin texture, ideal for normal to dry and mature skin types.
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    Lotion P50V

    Vitamin-Enriched Exfoliating Toner

    $45.00
    $45.00
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  • Biologique Recherche Serum Complexe Iribiol, Purifying & Rebalancing Face Serum Biologique Recherche Serum Complexe Iribiol, Purifying & Rebalancing Face Serum
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    Serum Complexe Iribiol

    Purifying & Rebalancing Face Serum

    $50.00
    $50.00
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  • biologique recherche iso placenta
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    Creme ISO-Placenta

    Regenerating Face Cream

    $100.00
    $100.00

    Add to cart
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  • Biologique Recherche Serum Iso-Placenta, regenerating serum for the face. Size 1.0 fl.oz Biologique Recherche Serum Iso-Placenta, regenerating serum for the face. Size 0.3 fl.oz
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    Serum Iso-Placenta

    Skin-Renewing Serum for Post-Acne Healing

    $60.00
    $60.00
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  • Biologique Recherche Lait E.V. moisturizing and lipd restoring makeup remover 8.4 fl.oz Biologique Recherche Lait E.V. moisturizing and lipd restoring makeup remover 5.1 fl.oz
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    Lait E.V.

    Deeply Hydrating Cleansing Milk

    $35.00
    $35.00
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  • Serum Elastine Biologique Recherche Serum Elastine, line correcting anti-aging serum Size 0.3 fl.oz
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    Serum Elastine

    Anti-Wrinkle Serum

    $60.00
    $60.00
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  • Biologique Recherche Lait S.R. Cleanser – gentle gel-cream formula for oily and combination skin. Size8.4 fl.oz Biologique Recherche Lait S.R. Cleanser – gentle gel-cream formula for oily and combination skin. 5.1 fl.oz
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    Lait S.R.

    Purifying, Rebalancing Cleanser

    $30.00
    $30.00
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  • Creme Hydravit&
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    Creme Hydravit's

    Hydrating and Revitalizing Face Cream

    $135.00
    $135.00

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  • Lait Dermo-S cleansing milk in a white bottle with a gold pump dispenser, featuring a white label with blue Biologique Recherche branding, shown on a white background. The gentle formula soothes and cleanses sensitive skin without irritation. Lait Dermo-S
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    Lait Dermo-S

    Gentle Cleansing Milk for Fragile or Sensitive Skin

    $30.00
    $30.00
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  • P-Tiox Cream

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  • Biologique Recherche Creme Elastine
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    Creme Elastine

    Anti-Wrinkle Face Cream

    $100.00
    $100.00

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  • COLLAGENE ORIGINEL COLLAGENE ORIGINEL
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    COLLAGENE ORIGINEL

    Advanced collagen-boosting anti-aging serum

    $85.00
    $85.00
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  • Biologique Recherche Creme Collagene
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    Creme Collagene

    Anti-Aging Face cream

    $100.00
    $100.00

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  • Oligo-Proteines Marines Serum Oligo-Proteines Marines Serum
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    Oligo-Proteines Marines Serum

    Face Serum for Dull Skin, Anti-Dark Circle Serum

    $50.00
    $50.00
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  • Biologique Recherche Creme Contour Yeux et Levres Biofixine
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    Creme Contour Yeux et Levres Biofixine - 15 mL

    Lifting Eye & Lip Contour Cream

    $180.00
    $180.00

    Add to cart
  • Serum Amniotique VG Serum Amniotique VG
    biologique recherche
    Serum Amniotique VG

    Hydrating & Revitalizing Serum for Dehydrated Skin

    $85.00
    $85.00
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  • Serum Progeskin Serum Progeskin
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    Serum Progeskin

    Anti-Aging Face Serum that Regulates key aging proteins

    $85.00
    $85.00
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  • BioKiss Lip Balm
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    BioKiss Lip Balm

    Hydrating and Regenerating Lip Balm

    $75.00
    $75.00

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  • Biologique Recherche Crème VG Derm
    biologique recherche
    Creme VG Derm

    Deep Moisture Cream for Dry, Sensitive Skin

    $135.00
    $135.00

    Add to cart
  • Shop Rescue Spa Biologique Recherche Crème PIGM 400 brightening and dark spots correcting face cream in a white jar with gold trim.
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    Creme PIGM 400

    Brightening Face Cream

    $330.00
    $330.00

    Add to cart
  • Serum A-Glyca Biologique Recherche Serum A-Glyca – anti-glycation serum that firms skin and reduces deep wrinkles. Size 0.3 fl.oz
    biologique recherche
    Serum A-Glyca

    Anti-Aging Face Serum

    $85.00
    $85.00
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  • Biologique Recherche Creme Adn Metamorphique | Shop Rescue Spa
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    Creme Adn Metamorphique

    Firming & Tightening Face Cream

    $230.00
    $230.00

    Add to cart
  • Serum Liposmose Biologique Recherche Liposmose – anti-puffiness eye serum for under-eye bags and tired eyes. Size 0.3 fl.oz
    biologique recherche
    Serum Liposmose

    Eye Serum for Puffiness and Fatigue

    $50.00
    $50.00
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  • Serum Extraits Tissulaires Biologique Recherche Serum Extraits Tissulaires – Glass serum bottle with gold cap containing brown liquid, featuring a white label with dark blue Biologique Recherche branding, shown on a white background. Size 0.3
    biologique recherche
    Serum Extraits Tissulaires

    Moisturizing & Regulating Serum

    $50.00
    $50.00
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  • White tube of Biologique Recherche Emulsion Originelle Régénérante face cream standing upright on a white background.
    biologique recherche
    Emulsion Originelle Regenerante

    Soothing Face Cream

    $195.00
    $195.00

    Add to cart
  • Travel Size Lait VIP O2 Cleanser (New Formula) + Lotion P50 Shop Rescue Spa Biologique Recherche travel duo featuring Lait VIP O2 cleanser and Lotion P50 toner in 1.7 oz bottles.
    biologique recherche
    Travel Size Lait VIP O2 Cleanser (New Formula) + Lotion P50

    $80.00
    $80.00
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  • Serum Matriciel Visage – Blue glass bottle of Biologique Recherche&
    biologique recherche
    Serum Matriciel Visage

    Tightening and Lifting Face Serum

    $300.00
    $300.00

    Add to cart

Why Biologique Recherche


Biologique Recherche is a professional-grade, clinical skincare line founded on the principle of "Skin Instants©." Unlike brands that categorize skin as simply dry or oily, Biologique Recherche recognizes that your skin changes daily based on climate, stress, and hormones.

The Rescue Spa Heritage
As the original U.S. partner to introduce Biologique Recherche to American clients over 20 years ago, Rescue Spa remains the definitive authority on the brand. We use these professional-grade formulas in our treatment rooms daily because they deliver the visible, long-term transformations our clients expect.

The Biologique Recherche Routine: A Step-by-Step Guide

To achieve the best results, Biologique Recherche products should be applied in a specific sequence. Every formula is cold-formulated to preserve the potency of its active biological extracts, ensuring your skin receives the highest level of care.

  1. Cleanse (The Preparation Phase): Begin with a cleansing milk tailored to your needs, Lait VIP O2 for oxygenating, Lait EV for nourishing, Lait S.R for balancing, or Lait Dermo-S for soothing. These non-stripping formulas remove impurities while respecting the skin’s delicate lipid barrier.
  2. Exfoliate & Balance (The Initialization Phase): This is the most critical step. Apply your specific Lotion P50 formula to gently exfoliate, hydrate, and rebalance the skin’s pH. This stage primes the epidermis to fully absorb the active ingredients that follow.
  3. Treat (The Active Phase): Layer high-concentration Biologique Recherche Serums to target specific concerns with immediate precision. These "raw" active fluids are designed to be pressed into the skin to address everything from deep hydration to purifying congestion.
  4. Target & Finish (The Protection Phase): Seal in your treatment with a Targeted Cream to address your primary skin goal. For the ultimate glow, apply a Finishing Serum as the final step to protect the skin and lock in your active ingredients.

FAQ

Where can I buy authentic Biologique Recherche?

You can shop Biologique Recherche at Rescue Spa—online or in-store. We’re the original U.S. spa and online retailer to introduce the brand to American clients, and we carry a curated assortment of authentic products.

How soon will I see results with Biologique Recherche?

Many people notice improved glow and smoother texture within 1–2 weeks, with more visible changes in clarity, tone, hydration, and firmness typically building over 4–8 weeks (depending on your routine and skin concern).

What is a Biologique Recherche routine?

A simple BR routine is usually built in layers: cleanse → Lotion P50 → targeted serums → moisturizer/cream → mask (a few times per week). The idea is to personalize each step to your skin’s current needs—your “Skin Instant.”

What is Lotion P50, and do I really need it?

Lotion P50 is the brand’s most iconic product. Think of it as the step that helps everything else work better: it refines texture, boosts clarity and glow, and supports a smoother-looking complexion. Many routines are built around it.

Is Biologique Recherche good for acne or congestion?

Yes. It’s a favorite for congestion and breakouts because it helps balance oil, refine pores, and support clearer skin—especially when paired with the right mask, serum, and moisturizer.

Can it help with dryness and dehydration?

Absolutely. There are excellent hydration-supporting serums and creams that help restore comfort and bounce without feeling heavy.

What if my skin is sensitive?

Biologique Recherche can work beautifully for sensitive skin when you choose the right products. There are calming, barrier-supporting options that help reduce redness and reactivity.

How do I choose what’s right for me?

Biologique Recherche is built around the idea that your skin changes. If you’re not sure where to start, you can shop by category (cleansers, P50, serums, moisturizers, masks) or by your main concern—hydration, acne, sensitivity, tone, or firmness—and we also offer skincare consultations at Rescue Spa to help you build the right routine for your Skin Instant.