Biologique Recherche

Serum Vivant

Targeted Blemish Control Serum

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    $195.00
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    $195.00
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    Size
    • Clarifying
    • Balancing
    • Smoothing
    • Strengthening

    Daily clarity for blemish-prone skin—without compromising the barrier.

    Free ground shipping on U.S. orders over $50

    Complimentary Samples with Every Order

    Complimentary skincare consultation

    The Details

    Sérum Vivant, also written Serum Vivant, is a daily leave-on serum from Biologique Recherche, formulated to visibly correct persistent adult blemishes and the redness that comes with them. It works by rebalancing the skin rather than stripping it, using a prebiotic, a postbiotic and a fermentation-derived purifier so that congestion clears without the dryness and peeling that usually come with blemish care. It is the daily counterpart to Masque Vivant, the fermented yeast mask that made Biologique Recherche a name with congested skin.

    Why Adult Blemishes Are Different

    Blemishes after 25 sit on skin that is more fragile and slower to recover than teenage skin, which is why the products that worked at 16 often make things worse at 35. Research cited by Biologique Recherche puts persistent blemishes at roughly two in five women after the age of 25. Sérum Vivant was developed for exactly that skin: strong enough to correct, gentle enough to use twice a day indefinitely.

    Key Benefits

    • Visibly reduces persistent blemishes and post-breakout redness

    • Regulates excess sebum for a more balanced, less shiny complexion

    • Refines uneven skin texture

    • Supports the skin barrier and microbiome rather than compromising them

    • Comfortable enough for daily long term use, including on sensitive skin

    The Three Actives

    Yeast Extract, a postbiotic. The signature Vivant active and the same fermented yeast at the center of Masque Vivant. Targets blemish related redness and supports blemish-prone skin.

    Inulin, a prebiotic. Feeds the skin existing microbial balance so the barrier stays resilient while blemishes clear.

    Polylysine, biotech derived. A gentle purifier that reduces surface impurities without the irritation of harsher blemish actives.

    Clinical Results

    Applied twice daily, results build progressively.

    • At 14 days: 27 percent reduction in excess sebum and 19 percent more refined texture

    • At 28 days: 42 percent reduction in persistent blemishes, 21 percent reduction in blemish related redness, and 19 percent improvement in skin barrier strength measured by reduced water loss

    Instrumental measurement and clinical scoring across three studies of 19 to 21 volunteers with combination to oily, blemish prone skin, half of whom had sensitive skin, applying twice daily.

    Texture and Sensory Signature

    Light, watery and faintly gel like. It absorbs in seconds and leaves no greasy finish. The brown color and the distinctive scent both come from the fermented yeast extract and are left unmasked on purpose. If you have used Masque Vivant, you already know them. They are the signature of the Vivant range and a signal that the ferment is present at a real concentration.

    Sérum Vivant or Masque Vivant

    The same ferment working on two different rhythms. Masque Vivant is a rinse off mask used one to three times a week for 15 minutes, deep purifying and resetting congestion with results visible after a single use. Sérum Vivant is a leave on serum used twice daily, correcting persistent blemishes and redness progressively, with measurable results at 14 days and substantial results at 28. The mask clears what is already there. The serum works on why it keeps coming back. Most people use both.

    Best For

    Skin types: oily, combination and blemish-prone skin, including sensitive skin.

    Skin concerns: persistent blemishes, excess oil, uneven texture, visible redness and congestion.

    Why We Recommend It

    Persistent blemishes need formulas that respect the barrier, and very few of them do. Sérum Vivant is one of the rare ones that corrects without stripping, which is why it layers into a full Biologique Recherche protocol rather than fighting it. Shop Rescue Spa is an authorized Biologique Recherche retailer, so every product reaches you exactly as it left the laboratory. If you are not sure where Serum Vivant belongs in your routine, book a Skin Instant consultation with a Rescue Spa esthetician.

    HOW TO USE

    Apply 2–4 drops to clean, dry skin over the face, neck, and décolleté morning and evening (AM/PM). Gently massage the serum into the skin using upward strokes until fully absorbed.

    Use after cleansing and before moisturizer. In the morning, finish with a broad-spectrum sunscreen. Suitable for both professional treatment protocols and daily at-home skincare routines.

    How to open serum:

    Helpful tip to maintain the integrity of the product, Biologique Recherche serums have a uniquely customized applicator that must be manually secured to the bottle. We understand that this could be a bit tricky, especially if you are opening a serum for the first time. We made a handy video to guide you through the process: How To Open Biologique Recherche Serum Vials


    How To Use Help Image
    INGREDIENTS

    Key Ingredients

    Yeast Extract (Postbiotic)
    A signature postbiotic that helps visibly reduce blemish-related redness while supporting a healthier-looking skin microbiome.

    Inulin (Prebiotic)
    A prebiotic that helps maintain a balanced skin microbiome and supports a stronger, more resilient skin barrier.

    Polylysine (Fermentation-Derived)
    A fermentation-derived ingredient that helps purify the skin, reduce excess impurities, and support a clearer-looking complexion.

    All Ingredients

    WATER (AQUA), GLYCERIN, METHYLPROPANEDIOL, YEAST EXTRACT, PROPANEDIOL, INULIN, GLYCERYL CAPRYLATE/CAPRATE, LENS ESCULENTA (LENTIL) SEED EXTRACT, RHODOMYRTUS TOMENTOSA FRUIT EXTRACT, PUNICA GRANATUM PERICARP EXTRACT, PISTACIA LENTISCUS (MASTIC) GUM, BACILLUS FERMENT, ALTEROMONAS FERMENT EXTRACT, POLYLYSINE, PHYTIC ACID, MALTODEXTRIN, XANTHAN GUM, LECITHIN, GLYCERYL CAPRYLATE, PENTYLENE GLYCOL, CAPRYLIC/CAPRIC TRIGLYCERIDE, PHENETHYL ALCOHOL, CAPRYLYL GLYCOL, POTASSIUM SORBATE, PHENYLPROPANOL, SODIUM HYDROXIDE, SODIUM BENZOATE, LEVULINIC ACID.

    *Please Note: This ingredient list is subject to change. Please refer to the product packaging for the most up-to-date ingredient list.

    FAQS

    Who is Serum Vivant best for?
    Serum Vivant is best for oily, combination, and blemish-prone skin experiencing persistent breakouts, excess oil, visible redness, or uneven texture.

    How do I use Serum Vivant?

    Apply 2–4 drops to clean, dry skin on the face, neck, and décolleté morning and evening before moisturizer. Follow with sunscreen during the day.

    Is Serum Vivant suitable for sensitive or acne-prone skin?
    Yes. It is formulated to help reduce blemishes and excess oil while respecting the skin's natural barrier, making it suitable for sensitive, blemish-prone skin.

    When will I see results?
    In clinical and consumer testing, 95% of participants reported soothed skin after the first application, 90% reported less oily skin after 7 days, 75% noticed smoother-looking skin after 14 days, and after 28 days, clinical testing showed a 42% reduction in the appearance of persistent blemishes. Individual results may vary.

    What makes Serum Vivant different from other blemish serums?
    Serum Vivant combines targeted blemish care with microbiome-supporting ingredients to help reduce excess oil, refine skin texture, and improve skin comfort without over-drying.

    A 30ml glass vial of Biologique Recherche &
    A small glass bottle of Biologique Recherche Serum Vivant serum with a gold cap and cream-colored label, centered on a light gray background.
    Inside the Formula

    Nature's Power in Every Ingredient

    01
    Yeast Extract

    A signature postbiotic that helps visibly reduce blemish-related redness while supporting a healthier-looking skin microbiome.

    02
    Inulin

    A prebiotic that helps maintain a balanced skin microbiome and supports a stronger, more resilient skin barrier.

    03
    Polylysine

    A fermentation-derived ingredient that helps purify the skin, reduce excess impurities, and support a clearer-looking complexion.

    HOW TO APPLY

    Biologique Recherche Sérum Vivant: Benefits & How to Use

    In this video, we break down what Sérum Vivant does, its key skin benefits, and how to incorporate it into your daily skincare routine to help visibly improve blemishes, excess sebum, redness, and uneven texture while supporting the skin barrier.
    WATCH NOW
    From Our Treatment Rooms

    A treatment-room essential for keeping blemish-prone skin clear, balanced, and calm.”

    Danuta Mieloch
    Founder & Master Esthetician, Rescue Spa
    As seen inVOGUEW MAGAZINETHE NEW YORK TIMES

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