Skin Care - Serums

Serums are fast-absorbing skincare products designed to deliver a high concentration of active ingredients to the skin. They are typically used after cleansing and before moisturizing as part of a skincare routine. Curated by Rescue Spa skin experts, this Facial Serums collection features best-selling, luxury formulas known for high-performance, high-concentration actives from brands such as Biologique Recherche, Valmont, Environ, iS Clinical, and MBR Medical Beauty Research.

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  • A 30ml glass vial of Biologique Recherche & A small glass bottle of Biologique Recherche Serum Vivant serum with a gold cap and cream-colored label, centered on a light gray background.
    biologique recherche
    Serum Vivant

    Targeted Blemish Control Serum

    $85.00
    $85.00
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  • Shop Rescue Spa Biologique Recherche Serum Complexe Iribiol purifying face serum in a glass bottle with gold cap. Shop Rescue Spa Biologique Recherche Serum Complexe Iribiol purifying face serum in a small glass vial with gold cap.
    biologique recherche
    Serum Complexe Iribiol

    Purifying & Rebalancing Face Serum

    $50.00
    $50.00
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    Esthetician's Favorite
  • Shop Rescue Spa Biologique Recherche Serum Iso-Placenta regenerating face serum in a glass bottle with gold cap. Shop Rescue Spa Biologique Recherche Serum Iso-Placenta 8ml regenerating face serum in a glass vial with gold cap.
    biologique recherche
    Serum Iso-Placenta

    Skin-Renewing Serum for Post-Acne Healing

    $60.00
    $60.00
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  • Shop Rescue Spa SkinCeuticals C E Ferulic antioxidant vitamin C serum in a brown glass dropper bottle C E Ferulic
    skinceuticals
    C E Ferulic

    Advanced vitamin C serum for environmental defense

    $185.00
    $185.00

    Add to cart
    Esthetician's Favorite
  • Shop Rescue Spa Collagene Originel 3D redensifying anti-aging face serum in a glass bottle with a gold cap Shop Rescue Spa Collagene Originel 3D redensifying anti-aging face serum in a small blue glass bottle with gold cap.
    biologique recherche
    COLLAGENE ORIGINEL

    Advanced collagen-boosting anti-aging serum

    $85.00
    $85.00
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  • Shop Rescue Spa Biologique Recherche Oligo-Proteines Marines brightening face serum in a glass bottle with gold cap. Shop Rescue Spa Oligo-Proteines Marines brightening serum in a small glass vial with a gold cap for dark circles.
    biologique recherche
    Oligo-Proteines Marines Serum

    Face Serum for Dull Skin, Anti-Dark Circle Serum

    $50.00
    $50.00
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  • Shop Rescue Spa Biologique Recherche Amniotique VG hydrating serum in a clear glass bottle with a gold cap. Shop Rescue Spa Biologique Recherche Amniotique VG hydrating serum in an 8ml glass bottle with a gold cap.
    biologique recherche
    Serum Amniotique VG

    Hydrating & Revitalizing Serum for Dehydrated Skin

    $85.00
    $85.00
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  • Shop Rescue Spa Danucera Mega Serum in a gold bottle with a white cap, a powerful anti-aging skincare treatment. Shop Rescue Spa Danucera Mega Serum bottle and box in gold packaging for anti-aging skincare
    danucera
    Mega Serum

    Advanced serum for firmness, radiance, and hydration

    $165.00
    $165.00
    Add to cart
    Esthetician's Favorite
  • Shop Rescue Spa Biologique Recherche Progeskin anti-aging face serum in a 30ml red glass bottle with a gold cap. Shop Rescue Spa Biologique Recherche Progeskin anti-aging serum in a small 8ml glass bottle with a gold cap.
    biologique recherche
    Serum Progeskin

    Anti-Aging Face Serum that Regulates key aging proteins

    $85.00
    $85.00
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  • Shop Rescue Spa iS CLINICAL Pro-Heal Serum Advance+ in an amber glass bottle with a white dropper cap. Shop Rescue Spa iS CLINICAL Pro-Heal Serum Advance+ in an amber glass bottle with a white dropper cap.
    is clinical
    Pro-Heal Serum Advance

    Vitamin C and antioxidant serum for repair

    $104.00
    $104.00
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  • Shop Rescue Spa Biologique Recherche Serum A-Glyca anti-aging face serum in a glass bottle with a gold cap. Shop Rescue Spa Biologique Recherche Serum A-Glyca anti-aging serum in a small glass vial with a gold cap.
    biologique recherche
    Serum A-Glyca

    Anti-Aging Face Serum

    $85.00
    $85.00
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  • Shop Rescue Spa Biologique Recherche Serum Extraits Tissulaires in a 30ml glass bottle for deep skin hydration. Shop Rescue Spa Biologique Recherche Serum Extraits Tissulaires moisturizing face serum in a small glass vial
    biologique recherche
    Serum Extraits Tissulaires

    Moisturizing & Regulating Serum

    $50.00
    $50.00
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  • Shop Rescue Spa Biologique Recherche Liposmose eye serum in a clear glass bottle with a gold cap Shop Rescue Spa Biologique Recherche Liposmose eye serum in a small glass bottle with a gold cap.
    biologique recherche
    Serum Liposmose

    Eye Serum for Puffiness and Fatigue

    $50.00
    $50.00
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  • Shop Rescue Spa Serum Matriciel Visage tightening and lifting face serum in a 30ml blue glass pump bottle.
    biologique recherche
    Serum Matriciel Visage

    Tightening and Lifting Face Serum

    $300.00
    $300.00

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  • Shop Rescue Spa Biologique Recherche Colostrum VG serum in a 30ml glass bottle for deep skin hydration. Shop Rescue Spa Biologique Recherche Colostrum VG serum in a small glass vial with a gold cap for dry skin.
    biologique recherche
    Serum Colostrum VG

    Serum for Dehydrated, Dry and Compromised Skin

    $85.00
    $85.00
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  • Shop Rescue Spa Environ Youth EssentiA Intensive Serum 4 Plus in a silver and blue airless pump bottle.
    environ
    Youth EssentiA Intensive Serum 4 Plus (Formerly C-Quence)

    High-strength anti-aging serum with vitamins A, C, E

    $170.00
    $170.00

    Add to cart
  • Shop Rescue Spa Biologique Recherche Serum Dermopore in a clear glass bottle with a gold cap for pore tightening. Shop Rescue Spa Biologique Recherche Serum Dermopore for pore tightening in a small glass bottle with gold cap
    biologique recherche
    Serum Dermopore

    Refining, Pore-Tightening Face Serum

    $60.00
    $60.00
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  • Biologique Recherche Serum PIGM 400 brightening and dark spots correcting serum for face in a white pump bottle. Biologique Recherche Serum PIGM 400 brightening and dark spots correcting serum for face, 0.3 fl. oz.
    biologique recherche
    Serum PIGM 400

    Brightening, Anti-Dark Spot Serum

    $115.00
    $115.00
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  • Shop Rescue Spa Biologique Recherche Serum VG Tensil firming and tightening botanical face serum in a 30ml glass bottle. Shop Rescue Spa Biologique Recherche Serum VG Tensil firming botanical face serum in a small glass vial
    biologique recherche
    Serum VG Tensil

    Firming & Tightening Serum

    $85.00
    $85.00
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  • Active Serum Active Serum
    is clinical
    Active Serum

    Multi-action serum for aging and blemish-prone skin

    $96.00
    $96.00
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  • Environ Youth EssentiA C-Quence Serum 3 bottle on a white background, anti-aging vitamin A face serum
    environ
    Youth EssentiA C-Quence Serum 3

    Medium-strength anti-aging serum with vitamins A, C, E

    $150.00
    $150.00

    Add to cart
  • Shop Rescue Spa Environ Youth EssentiA C-Quence Serum 1 in a silver and blue airless pump bottle for anti-aging.
    environ
    Youth EssentiA C-Quence Serum 1

    Introductory anti-aging serum with vitamins A, C, E

    $138.00
    $138.00

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  • Shop Rescue Spa Biologique Recherche Serum Erythros anti-redness face serum in a 30ml white dropper bottle.
    biologique recherche
    Serum Erythros

    Strengthening, redness reducing Serum

    $140.00
    $140.00

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  • Shop Rescue Spa Serum Grand Millesime youth-enhancing face serum in a blue glass bottle with a gold cap. Shop Rescue Spa Serum Grand Millesime youth-enhancing face serum in a blue glass bottle with a gold cap.
    biologique recherche
    Serum Grand Millesime

    Hydrating Anti-Aging Elixir with Antioxidants & Hyaluronic Acid

    $115.00
    $115.00
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  • Shop Rescue Spa Le Grand Serum radiance-boosting finishing serum in a gold bottle for hydrated and glowing skin Shop Rescue Spa Le Grand Serum 8ml bottle, a luxurious radiance-boosting facial finishing serum in gold packaging.
    biologique recherche
    Le Grand Serum

    Anti-Aging Finishing Serum

    $250.00
    $250.00
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  • Shop Rescue Spa Environ Vita Enriched Colostrum Gel in a 30ml airless pump bottle for soothing sensitive skin
    environ
    Vita Enriched Colostrum Gel

    Hydrating Soothing Serum

    $76.00
    $76.00

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  • Shop Rescue Spa iS Clinical Super Serum Advance+ vitamin C brightening serum in an amber glass dropper bottle Shop Rescue Spa iS Clinical Super Serum Advance+ vitamin C serum in an amber glass bottle with a dropper cap.
    is clinical
    Super Serum Advance+

    Vitamin C Serum for Wrinkles and Brightening

    $104.00
    $104.00
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  • Shop Rescue Spa Environ Youth EssentiA C-Quence Serum 2 in an airless silver and blue pump dispenser bottle.
    environ
    Youth EssentiA C-Quence Serum 2

    Medium-strength anti-aging serum with vitamins A, C, E

    $142.00
    $142.00

    Add to cart
  • Shop Rescue Spa MBR Modukine Serum in a 50ml airless pump bottle for sensitive and rosacea-prone skin Shop Rescue Spa Modukine Serum in an airless pump bottle with its matching white and pink product box.
    mbr medical beauty research
    Modukine Serum

    Barrier-strengthening serum for redness and sensitivity

    $240.00
    $240.00

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  • Biologique Recherche Sérum T.E.W.L. 1.0 fl.oz – A white skincare bottle with a branded white label featuring dark blue lettering and gold accents, displayed upright on a white background. This intensive hydrating and barrier-repair serum is designed to prevent trans-epidermal water loss and deeply nourish dehydrated skin. Biologique Recherche Sérum T.E.W.L. 0.3 fl.oz – A smaller white serum bottle with a branded white label featuring dark blue lettering and gold accents, shown upright on a white background. This intensive treatment helps prevent moisture loss and restore comfort to dry, dehydrated, or compromised skin.
    biologique recherche
    Serum T.E.W.L.

    Intense Hydration & Lipid Barrier Repair Serum

    $85.00
    $85.00
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  • Shop Rescue Spa iS Clinical Hydra-Cool Serum in a blue glass bottle with a pump dispenser for soothing hydration. Hydra-Cool Serum
    is clinical
    Hydra-Cool Serum

    Hydrating and Cooling antioxidant serum

    $70.00
    $70.00
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  • Shop Rescue Spa SkinCeuticals P-Tiox peptide serum in a dark glass dropper bottle for wrinkle correction. Shop Rescue Spa SkinCeuticals P-Tiox peptide serum in a blue glass dropper bottle with an Allure award seal.
    skinceuticals
    P-Tiox Peptide Serum

    Wrinkle-Modulating Serum for Radiant, Smooth Skin

    $150.00
    $150.00
    Add to cart
  • Hyaluronic Serum Shop Rescue Spa Dr. Barbara Sturm Hyaluronic Serum in a white 30ml box for intensive skin hydration.
    dr barbara sturm
    Hyaluronic Serum

    Hyaluronic acid serum for long-lasting hydration

    $325.00
    $325.00
    $325.00

  • Shop Rescue Spa MBR Cross Lift Serum Ultrapeptide in a silver airless pump bottle with a green label
    mbr medical beauty research
    Cross Lift Serum Ultrapeptide

    Advanced Tightening and Smoothing serum for lines and wrinkles

    $530.00
    $530.00

    Add to cart
  • Shop Rescue Spa Vintner& Active Botanical Serum
    vintner's daughter
    Active Botanical Serum

    Botanical Oil to Moisturize, Soothe, Revitalize

    $215.00
    $215.00

    Add to cart

Facial Serums for Targeted Skin Care


Our Facial Serums collection is curated by our experts at Rescue Spa and brings together effective, high-performing serums from multiple trusted brands. Facial serums are formulated with concentrated active ingredients and are typically used after cleansing (and toner, if used) and before moisturizing. This collection includes serums designed to address a wide range of skincare needs, including hydration, brightening, firming, smoothing, calming, and breakout support, with options suitable for different skin types and routines.

Serum Types and Key Ingredients

We carry a variety of serum types formulated with targeted ingredients such as hyaluronic acid for hydration, vitamin C and antioxidants for radiance, peptides and firming actives for visible signs of aging, exfoliating acids for texture and clarity, and soothing ingredients for sensitive or reactive skin. These formulas are designed to layer easily into both morning and evening skincare routines.

Trusted Luxury Serum Brands We Carry

Our Facial Serums collection features best-selling, luxury formulas known for advanced, active-rich compositions from brands we trust, including Biologique Recherche, Valmont, Environ, iS Clinical, and MBR Medical Beauty Research. Each serum is selected for its performance, formulation quality, and real skin benefits.

Related Collections

Facial Cleansers | Toners | Moisturizers | Anti-Aging Skin Care

Shop Our Most Popular Serum Brands

Biologique Recherche | Valmont | Environ | iS Clinical | MBR Medical Beauty Research

FAQ

What does a facial serum do?

A facial serum delivers concentrated active ingredients to target specific skin concerns such as dehydration, uneven tone, fine lines, or breakouts.

When should we apply a serum?

Apply serum after cleansing and toning, and before moisturizer.

Can we use more than one serum?

Yes. Serums can be layered or alternated depending on your skin’s needs and time of day.

Are facial serums suitable for all skin types?

Yes. We offer facial serums formulated for dry, oily, sensitive, acne-prone, and mature skin.