• Biologique Recherche Sérum T.E.W.L. 1.0 fl.oz – A white skincare bottle with a branded white label featuring dark blue lettering and gold accents, displayed upright on a white background. This intensive hydrating and barrier-repair serum is designed to prevent trans-epidermal water loss and deeply nourish dehydrated skin.
  • Biologique Recherche Sérum T.E.W.L. 0.3 fl.oz – A smaller white serum bottle with a branded white label featuring dark blue lettering and gold accents, shown upright on a white background. This intensive treatment helps prevent moisture loss and restore comfort to dry, dehydrated, or compromised skin.
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Biologique Recherche

Serum T.E.W.L.

Intense Hydration & Lipid Barrier Repair Serum

    $210.00
    $210.00
    or
    Shipping calculated at checkout.

    Free ground shipping on U.S. orders over $50

    Available in Philadelphia and New York

    Complimentary Samples with Every Order

    Size
    Description

    A high-performance serum that delivers deep hydration while repairing the skin’s barrier to prevent Trans-Epidermal Water Loss (TEWL). Serum T.E.W.L. is specially formulated for very dry, dehydrated, or compromised skin, replenishing essential lipids to relieve tightness, restore comfort, and smooth fine lines caused by dryness. This intensive treatment provides both instant relief and long-term protection, making it ideal for harsh weather, dry climates, or seasonal changes. With continued use, skin feels softer, more supple, and visibly healthier.

    What does it do?
    Deeply nourishes, repairs the skin barrier, and protects against dehydration while restoring long-lasting comfort.

    Benefits

    • Intensely hydrates and replenishes lipid-deficient skin
    • Prevents Trans-Epidermal Water Loss (TEWL)
    • Strengthens the protective skin barrier
    • Reduces fine dehydration lines
    • Provides immediate and lasting comfort
    • Ideal for winter dryness or harsh climates

    Skin Types
    Dry, very dry, or lipid-deficient skin.

    Skin Concerns
    Dehydration, tightness, flakiness, weakened barrier, fine lines from dryness.

    Key Ingredients

    • Lipid-Replenishing Actives – restore and strengthen the barrier
    • Hydrating Complex – boosts moisture retention
    • Protective Agents – shield skin from environmental stressors
    HOW TO USE

    Apply a few drops of Sérum T.E.W.L. to clean skin as the final step in your skincare routine, especially in the evening. Can be used alone or mixed with your favorite cream for extra nourishment.

    Pro Tip: For maximum hydration, apply over a water-based serum like Sérum Amniotique VG or Sérum Extraits Tissulaires.

    Helpful tip to maintain the integrity of the product, Biologique Recherche serums have a uniquely customized applicator that must be manually secured to the bottle. We understand that this could be a bit tricky, especially if you are opening a serum for the first time. We made a handy video to guide you through the process: How To Open Biologique Recherche Serum Vials.


    How To Use Help Image
    INGREDIENTS

    COCO-CAPRYLATE/CAPRATE, SESAMUM INDICUM (SESAME) SEED OIL, APRICOT KERNEL OIL PEG-6 ESTERS, MACADAMIA TERNIFOLIA SEED OIL, CAMELLIA JAPONICA SEED OIL, VACCINIUM MACROCARPON (CRANBERRY) SEED OIL, HIPPOPHAE RHAMNOIDES OIL, HIPPOPHAE RHAMNOIDES SEED OIL, GOSSYPIUM HERBACEUM (COTTON) SEED OIL, ETHYLHEXYL PALMITATE, RASPBERRY SEED OIL/TOCOPHERYL SUCCINATE AMINOPROPANEDIOL ESTERS, OLEA EUROPAEA (OLIVE) FRUIT OIL, HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL, LUFFA CYLINDRICA SEED OIL, SUNFLOWER SEED OIL GLYCERIDES, SIMMONDSIA CHINENSIS (JOJOBA) SEED EXTRACT, ROSMARINUS OFFICINALIS (ROSEMARY) LEAF EXTRACT, SALICORNIA HERBACEA EXTRACT, UNDARIA PINNATIFIDA EXTRACT, CANANGA ODORATA FLOWER OIL, CITRUS AURANTIUM AMARA (BITTER ORANGE) FLOWER OIL, TOCOPHEROL, PHYTOSTEROLS, DATEM, CAPRYLIC/CAPRIC TRIGLYCERIDE, LINALOOL, LIMONENE, BENZYL BENZOATE, FARNESOL, GERANIOL, BENZYL SALICYLATE.

    *Please Note: This ingredient list is subject to change. Please refer to the product packaging for the most up-to-date ingredient list.
    FAQS

    Q: Can I use Sérum T.E.W.L. daily?

    A:     Yes, this serum is especially beneficial when used daily in dry or cold climates. It’s best applied at night to help lock in moisture while you sleep.

    Q: Is this serum suitable for oily or acne-prone skin?

    A:     It’s best suited for very dry or dehydrated skin types. For oily or combination skin, we recommend consulting your esthetician before incorporating it into your routine.

    Q: Can it be layered with other serums?

    A:     Yes, it pairs well with water-based serums and is ideally applied last to seal in moisture.

    Q: Where can I buy Serum T.E.W.L.?

    A: It is available online at shoprescuespa.com and in-store at Rescue Spa Philadelphia or NYC locations.
    Biologique Recherche Sérum T.E.W.L. 1.0 fl.oz – A white skincare bottle with a branded white label featuring dark blue lettering and gold accents, displayed upright on a white background. This intensive hydrating and barrier-repair serum is designed to prevent trans-epidermal water loss and deeply nourish dehydrated skin.
    Biologique Recherche Sérum T.E.W.L. 0.3 fl.oz – A smaller white serum bottle with a branded white label featuring dark blue lettering and gold accents, shown upright on a white background. This intensive treatment helps prevent moisture loss and restore comfort to dry, dehydrated, or compromised skin.

    Recommended Products

    Overall rating: 5.0 / 5 from 17 reviews.

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    Reviews

    amazing

    "the hype is real- this serum is amazing. i’ve been suffering from especially tight, dry skin this winter and purchased this serum as a last resort. my skin feels so incredibly hydrated! this will be a new staple in my cold weather routine."

    — jackie (5/5)

    It Works!!

    "I recently started using T. E. W. L. after all of the rave reviews and I must say, once I put it on, I have that post-facial glow! It is thicker than most of BR's serums but it isn't sticky and really plumps my skin and its really never looked better. Will definitely have this on hand until summer, it's worth it"

    — Bridget W. (5/5)

    Good product

    "They make my skin hydrated in the winter. I will purchase again."

    — Lucy L. (5/5)

    This has saved my skin

    "This has saved my skin from the colder weather. I add a few drops to my moisturizer and no more dry skin issues."

    — Cnelson (5/5)

    Great product. Great hydration. It’s

    "Great product. Great hydration. It’s does say serum on the bottle when its really an oil."

    — Jennifer C. (5/5)

    One of my faves

    "I really enjoy this serum. I apply it as a last quintessential serum (usually I'll do 2-3) and before my moisturizer. The texture is creamy but it's light and absorbs quickly. It makes my skin look smooth and plumped up just a bit. It has a thicker texture than other initial serums but it is in no way thick, it's just perfect really."

    — Cory C. (5/5)

    Great texture woks well mixed

    "Great texture woks well mixed with Vivant masque. Can’t live without product."

    — Carolynne F. (5/5)

    Hydration!!

    "Great serum. Super hydrating."

    — Tbhughes (5/5)

    Loving it

    "My skin says THANK YOU for serum T. E. W. L. St. Louis is cold and dry and this amazing super serum has led to compliments like "Your skin is glowing " and " did you have. . . something done?'"

    — Dani S. (5/5)

    Winter must

    "My skin was looking very dry and dehydrated. I purchased the T. E. W. L serum and it worked wonders on my skin. Fine lines were drastically decreased and my skin looked great with and without makeup. Will buy again."

    — Katie S. (5/5)

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