Biologique Recherche

Creme ISO-Placenta

Regenerating Face Cream

    Regular price
    $100.00
    Regular price
    Sale price
    $100.00
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    Free ground shipping on U.S. orders over $50

    Available in Philadelphia and New York

    Complimentary Samples with Every Order

    Description

    Regenerating Face Cream

    Biologique Recherche Crème Iso-Placenta is a powerful, regenerative face cream designed to restore and revitalize skin damaged by acne, inflammation, or pigmentation. This innovative formula mimics the biological composition of human placenta to stimulate skin renewal, improve texture, and reduce redness.

    Enriched with biomimetic placenta peptides, stabilized Vitamin C, niacinamide (Vitamin B3), and yeast extract, it deeply nourishes the skin, encourages healthy tissue regeneration, and visibly diminishes the appearance of acne scars and dark spots. Skin is left smoother, brighter, and more even in tone.

    Ideal For:

    • Acne-prone or post-acne skin
    • Skin with acne scars or post-inflammatory hyperpigmentation
    • Dull, uneven, or textured skin
    • Sensitive skin in need of regeneration and soothing

    Key Benefits

    • Accelerates Skin Regeneration: Biomimetic placenta peptides support healing and skin renewal.
    • Fades Acne Scars & Pigmentation: Niacinamide and Vitamin C brighten and even out skin tone.
    • Soothes Redness & Irritation: Helps calm inflammation and reduce visible redness.
    • Deep Nourishment: Rich formula restores essential nutrients to rebuild the skin barrier.
    • Improves Texture & Clarity: Refines skin texture and boosts radiance.
    • Vegan-Friendly Formula: Mimics placenta without the use of animal-derived ingredients.

    Size: 1.7 oz.

     

    HOW TO USE

    Apply a small amount of product in the morning and/or at night to the entire face, neck and décolleté, after using your cleanser, toner and serums.

    Avoid the area around the eyes. For external use only.

    INGREDIENTS

    Biomimetic placenta, Maracuja Oil, Stabilized Vitamin C.

    WATER (AQUA), PROPYLENE GLYCOL, DICAPRYLYL CARBONATE, GLYCERIN, SUCROSE POLYSTEARATE, C10-18 TRIGLYCERIDES, CETYL ALCOHOL, GLYCERYL STEARATE CITRATE, PENTAERYTHRITYL TETRASTEARATE, 1,2-HEXANEDIOL, BORON NITRIDE, NIACINAMIDE, PASSIFLORA EDULIS SEED OIL, BETULA ALBA BARK EXTRACT, EQUISETUM ARVENSE EXTRACT, HEDERA HELIX (IVY) LEAF/STEM EXTRACT, FUCUS VESICULOSUS EXTRACT, CENTELLA ASIATICA EXTRACT, YEAST EXTRACT, BACILLUS/SOYBEAN FERMENT EXTRACT. HEXAPEPTIDE-11, OLIGOPEPTIDE-1, OLIGOPEPTIDE-2. OLIGOPEPTIDE-3. ASCORBYL GLUCOSIDE, ACETYL GLUTAMINE, FOLIC ACID, SODIUM HYALURONATE, LECITHIN, TOCOPHEROL, BUTYLENE GLYCOL, POLYACRYLATE CROSSPOLYMER-6, CAPRYLYL GLYCOL, SODIUM HYDROXIDE, SODIUM BENZOATE.

    *Please Note: This ingredient list is subject to change. Please refer to the product packaging for the most up-to-date ingredient list.

    FAQS

    Q: Is Crème Iso-Placenta suitable for sensitive skin?

    A: Yes, the formula is gentle and soothing, making it ideal for sensitive, reactive, or post-acne skin.

    Q: Can I use this cream if I have active acne?

    A: Yes. It supports healing and reduces inflammation, making it effective for both active acne and post-acne recovery.

    Q: How long does it take to see results?

    A: With consistent use, most users notice improvements in texture, brightness, and reduced redness within 2–4 weeks.

    Q: Is this product vegan?

    A: Yes. It contains biomimetic (synthetic) placenta peptides, offering the benefits of the placenta without animal-derived ingredients.

    Q: Can I use it with Vitamin C serums or exfoliants?

    A: Crème Iso-Placenta already contains stable Vitamin C. You can layer it with other products, but always follow your esthetician’s or skincare expert’s advice for the best results.

    biologique recherche iso placenta

    Recommended Products

    Overall rating: 3.625 / 5 from 24 reviews.

    AI Generated Review Summary

    Creme ISO-Placenta is a regenerative face cream that supports skin renewal and reduces redness and pigmentation. It is enriched with biomimetic placenta peptides, Vitamin C, and niacinamide, offering deep nourishment and improving skin texture. While some users report positive results, others mention breakouts or dryness.

    Summary topics

    • Hydration and Healing: 35%
    • Skin Improvement: 27%

    Review topics: [].

    Review highlights

    • "in the morning my skin feels velvety soft and hydrated."Alyssa
    • "I have used the old school creme placenta for two years religiously and love this new formula."Matt
    • "3-4 months later of using this every night and my skin is dramatically improved!"Alyssa

    Reviews

    Favorite

    "Favorite cream on the market. Does such a good job of hydrating."

    Yasmine (5/5)

    love this - does what it claims

    "Ive been trying to clear hormonal acne and the texture/redness/marks left over that started 1-2 yrs ago and this has been a key product in improving my skin. I have combo skin that is mildly sensitive. before i used this I broke out easily + daily and my skin looked a bit dehydrated and irritated. Someone at the rescue spa in nyc recommended this cream and gave me a sample. after just one night of use my skin was noticeably less red, less textured, and soft in the am. 3-4 months later of using this every night and my skin is dramatically improved! Im just refilling now and i have about a weeks worth left in case youre curious how long this will last. i should note i do also use azelaic acid and a benzyl peroxide wash as a mask, but i credit this moisturizer to keeping my texture smooth, minimizing post acne redness alongside the azelaic acid, improving overall quality of my skin (its less irritated looking and more even in tone/less red overall) and doing a great job moisturizing my combo skin without clogging pores. in the morning my skin feels velvety soft and hydrated. i dont wake up with an oily t zone nor do i feel any dryness. the product is a bit thicker than a gel style moisturizer but i did not find this to be an issue. consistent with many other BR products, this STINKS. I would never use this in the morning because of that. Its worth it imo and you definitely desensitize to the smell over time. its very mild to me now."

    Alyssa (5/5)

    Terrible compared to the original creme placenta

    "I love BR but they seem to be cutting costs and cutting corners and ruining products in the process. Miss the old creme placenta soo much. Iso planets is not good."

    Kinzie B. (1/5)

    BR Please Bring Back the Old Creme Placenta!

    "The new Creme Placenta is good but it's not great like the previous original Creme Placenta formula. Everyone I know who uses BR products misses the old Creme Placenta. BR, please bring back the original formula!"

    Kinzie B. (3/5)

    My miracle cream

    "I have post acne scars, hyper-pigmentation, and dehydrated facial skin. Started using Creme ISO-Placenta (free sample) and loved it the next morning after one use. I've been using for about 5 months now and noticed my scars and Hyper-pigmentation spots are fading and less noticeable. It's a miracle in the bottle for me."

    Mike B. (5/5)

    Cause Breakout - Dissapointed with new formula

    "The new formula is aweful. I had been using the old formula for a while and it kept my skin hydrated while didn’t cause breakout. Tried the new formula and it made my skin so oily, especially during summer months and I had bad breakout. It also didn’t hydrate my skin like the old one. Very disapointed in this change of formula!"

    Micdian (1/5)

    Not nearly as good as the original Creme Placenta

    "Creme Placenta was my all time favorite moisturizer. It nourished my skin in a way no other has. I used it for years! I'm heartbroken it is discontinued, especially considering that this "reformulated" version is really nothing like the original placenta creme. It didn't have any negative effects on my skin, but it also didn't do what I had come to love about the old placenta creme--almost like food for the skin. Nourishing and balancing. Simply heartbroken by this. If anyone has found something that is a good substitute for the Creme Placenta, please share!!"

    Katharine G. (3/5)

    Disappointing

    "I’m really disappointed they discontinued the original Crème Placenta. I have acne prone skin and this caused me to breakout. I loved the original. It had such a nice finish and was very calming. This new one is a totally different texture. These products are amazing and I love this brand but this is a no."

    Nathan B. (1/5)

    Love!

    "I never tried the original placenta cream so I cannot speak to how this stands up to that but I LOVE Creme ISO Placenta! It’s unlike any cream I’ve tried, it’s very lightweight with a gel like texture but still feels weirdly nourishing. I’ve been using in tandem with iso placenta serum and they have smoothed and healed my skin like no other. I have a scar on my chin from childhood that I’ve come to love and accept as part of my face but in the month and a half I’ve been using the iso line it’s began to shrink! I wasn’t even expecting that. It’s also incredibly smoothing in a way I’ve never experienced before. I will say to see the best results from BR products use the line exclusively as no one product can work miracles alone and get a consultation from a professional first to get the best products for your skin and desired results. At this point in time I can’t see myself using any other products period."

    Mariah (5/5)

    Nothing like the old creme placenta

    "I’m so disappointed BR updated creme placenta…this new version doesn’t feel nourishing like the original. BR please bring back the original!"

    Arosenberg (2/5)

    Q&A